UNC 926 hydrochloride

CAS No. 1184136-10-4

UNC 926 hydrochloride ( —— )

Catalog No. M17174 CAS No. 1184136-10-4

UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3.

Purity : 97%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 41 In Stock
10MG 71 In Stock
25MG 140 In Stock
50MG 250 In Stock
100MG 403 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    UNC 926 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3.
  • Description
    UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3. UNC-926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC-926 has not an effect on the binding of 53BP1 to H4K20me1.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    L3MBTL1
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    1184136-10-4
  • Formula Weight
    373.72
  • Molecular Formula
    C16H21BrN2O·HCl
  • Purity
    97%
  • Solubility
    ——
  • SMILES
    C1CCN(C1)C1CCN(CC1)C(=O)c1cc(ccc1)Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Herold JM, et al. Structure–activity relationships of methyl-lysine reader antagonists. MedChemComm. 2012;3(45):45–51.
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