UNC 926 hydrochloride
CAS No. 1184136-10-4
UNC 926 hydrochloride ( —— )
Catalog No. M17174 CAS No. 1184136-10-4
UNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3.
Purity : 97%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 41 | In Stock |
|
10MG | 71 | In Stock |
|
25MG | 140 | In Stock |
|
50MG | 250 | In Stock |
|
100MG | 403 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameUNC 926 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionUNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3.
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DescriptionUNC-926 inhibits L3MBTL1 (IC50: 3.9 μM). UNC-926 also exhibits a low micromolar affinity for L3MBTL3. UNC-926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC-926 has not an effect on the binding of 53BP1 to H4K20me1.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorL3MBTL1
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number1184136-10-4
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Formula Weight373.72
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Molecular FormulaC16H21BrN2O·HCl
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Purity97%
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Solubility——
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SMILESC1CCN(C1)C1CCN(CC1)C(=O)c1cc(ccc1)Br
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Herold JM, et al. Structure–activity relationships of methyl-lysine reader antagonists. MedChemComm. 2012;3(45):45–51.
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